Vitamin B12 deficiency - symptoms, causes and therapy | ApA guide

„Osoba drži bočicu vitamina B12 okruženu hranom bogatom B12, suplementima i medicinskim priborom, uz istaknuti naslov ‘Vitamin B12 – Sve što trebate znati’.“
„Prirodni izvori vitamina B12, uključujući goveđu jetru, losos, školjke, jaja, sir, jogurt, zob i suplemente, raspoređeni na svijetloj podlozi uz natpis B12 i ApA potpis.“
Foods richest in vitamin B12 - key foods for energy, blood count and a healthy nervous system.

Vitamin B12 deficiency - symptoms, causes and therapy are increasingly common topics in modern medicine and nutrition. This essential vitamin plays a key role in the formation of red blood cells, nervous system health, and energy. Recognizing early signs of deficiency is crucial for timely treatment and prevention of more serious complications

Modern eating habits, stress, and certain medical conditions have led to a significant increase in cases of B12 deficiency, so it is important to recognize early signs and respond in a timely manner.

For a deeper understanding of the link to anemia, it's helpful to read the explanation on the Mayo Clinic site
Mayo Clinic experts explain the link between anemia and vitamin B12, which can further help in understanding the symptoms.https://www.mayoclinic.org

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Take advantage of the holiday discount and strengthen your health with premium Omega-3 Arctic Sea.

How to recognize vitamin B12 deficiency? – Key symptoms

Vitamin B12 deficiency develops slowly and is often not recognized in time. Symptoms can be classified into two large groups: neurological i hematological.


🧠 Neurological and psychological symptoms

Vitamin B12 directly affects myelin sheath which protects the nerves. When B12 levels drop, damage to the peripheral and central nerves begins.

The most common symptoms:

  • Paresthesias – tingling, burning, numbness in the hands, legs or feet.
  • Ataxia – problems with balance and gait coordination.
  • Cognitive problems – poor memory, confusion, difficulty concentrating (often misinterpreted as dementia in the elderly).
  • Mood swings – irritability, anxiety, depression; sometimes even paranoia or psychosis.


😴 Hematological and general symptoms

B12 deficiency causes megaloblastic anemia — making large, ineffective red blood cells.

Main symptoms:

  • Chronic fatigue and weakness
  • Pale skin or light jaundice
  • Glossitis – smooth, red, painful tongue
  • Mouth ulcers
  • Rapid heartbeat and shortness of breath
  • Loss of appetite, bloating, indigestion

➡️ If you notice a combination of fatigue, tingling and problems with concentration — don't wait. This is a classic "red flag" of B12 deficiency.


🍽️ The best dietary sources of vitamin B12

„Namirnice bogate vitaminom B12 – losos, goveđa jetra, školjke, jaja, sir i gljive oko table s natpisom Vitamin B12.“

„"Health begins where the body gets what it naturally needs."“

B12 is almost exclusively found in foods of animal origin.

The richest natural resources:

GroceryWhy it is a great source of B12
Beef liverThe strongest natural source – up to 1,500% daily requirement in 100g
Shellfish (mussels, oysters)Highly concentrated B12 + minerals
Fatty fish (salmon, sardine, tuna)B12 + Omega-3 fatty acids
Beef and poultryStable and reliable input
Eggs and dairy productsMore easily digestible B12 for daily nutrition

🌱 Vitamin B12 for vegans and vegetarians

Plant-based foods do not contain B12, unless they are fortified.

Reliable sources for vegans:

  • Enriched cereals
  • Enriched vegetable milk (soy, almond, oat)
  • Nutritional yeast enriched with B12
  • Supplements (mostly needed daily)

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💉 Modern therapy of vitamin B12 deficiency

Treatment depends on the cause. Therapy is determined exclusively under the professional guidance of a doctor.

The most common causes of poor absorption:

  • Pernicious anemia - autoimmune attack on the intrinsic factor
  • Crohn's, celiac disease, gastritis – absorption impairment
  • Medications – metformin, proton pump inhibitors, H2 blockers
  • Age
  • Stomach and intestinal surgeries

Therapeutic options:

💊 1. High-dose oral supplements

They are used for milder deficits or for people with insufficient intake.

💉 2. Intramuscular injections (gold standard)

Most effective in absorption disorders.

  • initial phase: more frequent injections
  • then: monthly lifelong maintenance therapy

👃 3. Nasal sprays

Alternative for mild to moderate deficits.


📈 Forecast and long-term perspective

  • Hematological symptoms are improving after just a few weeks therapy.
  • Neurological symptoms may subside, but recovery may take time 6–12 months.
  • Long-term, untreated deficits can leave permanent damage — that's why early diagnosis is crucial.

Don't wait for vitamin B12 deficiency to affect your health and energy!

Get your blood count and vitamin B12 levels checked today.
Consult your doctor or nutritionist about optimal therapy and nutrition.

A healthy life begins with knowledge — ApA Nature • Knowledge • Inspiration 🌿


1️⃣ Have you ever experienced symptoms like chronic fatigue, tingling, or trouble concentrating, and didn't know what was causing them?

2️⃣ How often do you check your lab results – including your vitamin B12 level – and should you be doing it more often?

3️⃣ If you are vegan, vegetarian, or have digestive issues, have you ever considered preventative supplementation or a fortified diet?

✨ Think about these questions and share your experience in the comments. Your story can be a guide for someone.

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